Structure of PDB 8pdn Chain A

Receptor sequence
>8pdnA (length=339) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence]
DLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEILYAKHADY
KYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSQMLDIHGVEK
SWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLCVGALIFTK
LASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDLFEQKVYHR
SLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGVIARSSNNI
MLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLLSLANCPNF
ASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKE
3D structure
PDB8pdn Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
ChainA
Resolution4.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A K171 A173 S174 R185 R186 R189 Q250 G255 T257 W261 S314 I334 M337 Y338 R339 K150 A152 S153 R164 R165 R168 Q229 G234 T236 W240 S293 I313 M316 Y317 R318
BS02 rna A R186 R189 V190 S242 L243 N246 R165 R168 V169 S221 L222 N225
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pdn, PDBe:8pdn, PDBj:8pdn
PDBsum8pdn
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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