Structure of PDB 8pd8 Chain A

Receptor sequence
>8pd8A (length=1018) Species: 7668 (Strongylocentrotus purpuratus) [Search protein sequence]
AHAPKVIVFISGSCLFGAISRSLFKKLPIPYTVVLLILGAILGVVASNVP
LVEEHTRDVAHMDPHVLLQIFLPVLIFESAFAMDVHTFMRSFSQVCILAL
FGLVVASVLTAVLAMNLFNYNWNFSEAMMFGAIMSATDPVAVVALLKDLG
ASKQLGTIIEGESLLNDGCAIVIFNVFMKMVFFPQLTSTVGQNVLYFLQV
AVAGPLWGYAVAKVTVFFLSHIFNDALVEITITLAATYLTYYIGDIWLEV
SGVLAVVVLGLIVNAEKTSISPEVEVFLHRFWEMLAYLANTLIFMMVGVV
VTQKALVAVDKMDWFYLIILYLAITIIRGMVISLFSPILSRIGYGLTWRN
AVIMTWGGLRGAVGLALALVVENLAGNDVIGSKFLFHTAGIVVLTLVINA
TTIQTLLRILGMSDISIPKRLAMAGAVRRIHEGQNRTLNMLKSDRFLADA
DWDIATAACEISDPYSSPREFADMMEEARLRMLKAEKISYWKQFEHGMLA
REALRLLVQHAEVAADEKDQFILVDDLKKSWQIKGIYPWLKRKLEDLISH
HMAFEVTINIAIVLNIVPIIMEFVVQDKMLQKIEDALRISNYVFFVIYAI
EAIVKILGLGRHYIVSHWNKFDAFILVVALVDIIIAETSSIKVVKLFRLL
RGLRMLRLTKALIPKLILVVNGKINNQLSLGYDVGKGYIIGEEEVGKIID
RMVDNKKILRELKHISETGRLQVVKELGLLQREHPGIAVSVKTRQAIRTI
LNHSRETIHELQGAGLLDEMEAHKLELTVEIKMKRLMNAPSSIPPPPPEN
LLKNVSWLAGDMKLIDFIKARASLLHFDYGEVIVREGDESDGLFLIVSGL
VKLYGKSVFEDYLTVGNVIGEMGVLTKKPRNATVTCETTVQVYFITAEDM
NIAIDTFTLYPSLEYRLWRVVAIRIATPLIMEQMAFQGWTQEKVKLHLER
GYLVDLAESHFQFNIDATLEDVILINGTAYNAHTREEIRSPCLISRTVHK
LTFQYTATEEPRLFVVRN
3D structure
PDB8pd8 Structures of a sperm-specific solute carrier gated by voltage and cAMP.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A L1008 F1032 G1043 M1045 G1046 R1053 N1054 A1055 L853 F859 G870 M872 G873 R880 N881 A882
Gene Ontology
Molecular Function
GO:0015297 antiporter activity
GO:0015385 sodium:proton antiporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pd8, PDBe:8pd8, PDBj:8pd8
PDBsum8pd8
PubMed37880361
UniProtA3RL54|SL9C1_STRPU Sperm-specific sodium:proton exchanger (Gene Name=SLC9C1)

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