Structure of PDB 8pd6 Chain A

Receptor sequence
>8pd6A (length=181) Species: 9606 (Homo sapiens) [Search protein sequence]
SIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEDVPNNPERFD
TWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENG
VWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDG
SYIYTFNQLFSGLLRPYFFICDATPLILPPT
3D structure
PDB8pd6 Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YCB A D315 W332 P333 E357 W385 F449 I450 C451 D38 W52 P53 E77 W105 F169 I170 C171
BS02 MG A Q364 T366 L443 Q84 T86 L163
External links
PDB RCSB:8pd6, PDBe:8pd6, PDBj:8pd6
PDBsum8pd6
PubMed38116426
UniProtQ8NG06|TRI58_HUMAN E3 ubiquitin-protein ligase TRIM58 (Gene Name=TRIM58)

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