Structure of PDB 8pb8 Chain A

Receptor sequence
>8pb8A (length=311) Species: 181762 (Psilocybe cubensis) [Search protein sequence]
SHMASENLYFQGMHIRNPYRTPIDYQALSEAFPPLKPFVSVNADGTSSVD
LTIPEAQRAFTAALLHRDFGLTMTIPEDRLCPTVPNRLNYVLWIEDIFNY
TNKTLGLSDDRPIKGVDIGTGASAIYPMLACARFKAWSMVGTEVERKCID
TARLNVVANNLQDRLSILETSIDGPILVPIFEATEEYEYEFTMCNPPFYD
GAADMQTSDAPHSGTVIEMSTEGGESAFVAQMVRESLKLRTRCRWYTSNL
GKLKSLKEIVGLLKELEISNYAINEYVQGSTRRYAVAWSFTDIQLPEELS
RPSNPELSSLF
3D structure
PDB8pb8 Methyl transfer in psilocybin biosynthesis
ChainA
Resolution2.531 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A R75 G107 E131 V132 N183 E216 F226 R87 G119 E143 V144 N195 E218 F228
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0052907 23S rRNA (adenine(1618)-N(6))-methyltransferase activity
GO:0140381 4-hydroxytryptamine 4-phosphate methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0070475 rRNA base methylation
GO:0140380 psilocybin biosynthetic process
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8pb8, PDBe:8pb8, PDBj:8pb8
PDBsum8pb8
PubMed38548735
UniProtP0DPA9|PSIM_PSICU Psilocybin synthase (Gene Name=psiM)

[Back to BioLiP]