Structure of PDB 8p9w Chain A

Receptor sequence
>8p9wA (length=238) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSW
SCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAI
CLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLA
DLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
3D structure
PDB8p9w A vitamin D-based strategy overcomes chemoresistance in prostate cancer.
ChainA
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I270 K274 R280 I288 K292 P442 E446 E451 I56 K60 R66 I74 K78 P228 E232 E237
BS02 XDO A Y175 V262 S265 R302 S303 S306 W314 H333 H423 Y427 L440 F448 Y22 V48 S51 R88 S89 S92 W100 H119 H209 Y213 L226 F234
External links
PDB RCSB:8p9w, PDBe:8p9w, PDBj:8p9w
PDBsum8p9w
PubMed38982588
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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