Structure of PDB 8p5j Chain A

Receptor sequence
>8p5jA (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]
TETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQ
TLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAM
RTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPRANPNSIR
VKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTI
VYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPAATSAPLRQLLLALLQ
RNHKDRMDFDEFFHHPFLD
3D structure
PDB8p5j Crystal structures of ULK1 in complex with KCGS compounds
ChainA
Resolution2.164 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WYT A I22 G23 A44 M92 C95 G98 D99 D102 L145 D165 I15 G16 A37 M85 C88 G91 D92 D95 L138 D155
BS02 MG A E191 Y198 D199 H263 E181 Y188 D189 H253
External links
PDB RCSB:8p5j, PDBe:8p5j, PDBj:8p5j
PDBsum8p5j
PubMed
UniProtO75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 (Gene Name=ULK1)

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