Structure of PDB 8p5h Chain A

Receptor sequence
>8p5hA (length=269) Species: 9606 (Homo sapiens) [Search protein sequence]
TETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQ
TLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAM
RTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPANPNSIRV
KIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIV
YQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPAATSAPLRQLLLALLQR
NHKDRMDFDEFFHHPFLDA
3D structure
PDB8p5h Crystal structures of ULK1 in complex with KCGS compounds
ChainA
Resolution1.941 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XBJ A I22 A44 M92 C95 N96 G98 D99 Q142 L145 I15 A37 M85 C88 N89 G91 D92 Q135 L138
BS02 MG A E191 Y198 D199 H263 E180 Y187 D188 H252
BS03 MG A H136 D165 F166 F168 H129 D154 F155 F157
External links
PDB RCSB:8p5h, PDBe:8p5h, PDBj:8p5h
PDBsum8p5h
PubMed
UniProtO75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 (Gene Name=ULK1)

[Back to BioLiP]