Structure of PDB 8p43 Chain A

Receptor sequence
>8p43A (length=277) Species: 10090 (Mus musculus) [Search protein sequence]
SPHSLRYFTTAVSRPGLGEPRFIIVGYVDDTQFVRFDSDAENPRMEPRAR
WIEQEGPEYWERETWKARDMGRNFRVNLRTLLGYYNQSNDESHTLQWMYG
CDVGPDGRLLRGYCQEAYDGQDYISLNEDLRSWTANDIASQISKHKSEAV
DEAHQQRAYLQGPCVEWLHRYLRLGNETLQRSDPPKAHVTHHPRSEDEVT
LRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWAAVVVP
LGKEQYYTCHVYHEGLPEPLTLRWEPP
3D structure
PDB8p43 MHC-E is a convergent checkpoint ligand for LILRB1 on macrophages and during inflammation for NKG2A on lymphocytes
ChainA
Resolution2.43 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 M45 E63 K66 M70 F74 N77 Y84 L95 W97 Y99 S143 K146 E152 Q155 Y159 W167 Y171 Y7 M45 E63 K66 M70 F74 N77 Y84 L95 W97 Y99 S143 K146 E152 Q155 Y159 W167 Y171
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