Structure of PDB 8p0u Chain A

Receptor sequence

>8p0uA (length=621) Species: 11569 (Thogotovirus thogotoense) [Search protein sequence]

TDRPDHIDSRVWELSETQEDWITQVHGHVRRVVECWKYTICCLISNMHTH
RGAPQYDVFKWQDRSTIEWICSKKKVQYPERDTPDLYDNERAVAYKVLLV
SDLSDHSPTSGIYHDLAFNLEGEAEESCALVLRGSQLQDIKGFLCRALEW
VVSNNLTQEVVETISGEAKLQFSVGTTFRTLLKRDTDWDVIPTPRVEPNV
PRIEGRRWTQMKKLPLLKEKEGPPSPWRALLLGADSEYIVCPPGTDQEAI
SWIHSQSEIECIRESKSTPASVITCLTSSLQSFAEGNPVRSRIHEDIIAF
GINKKQEKKQSASSSASGEWKRAEYQVEEMSLPPWVEEEMVLLRSDQEDN
WIELEKNAIYTEVDGVAEGLVDKYIEIVGRTKVASVIEKWQIAATRTFSQ
LHTDRSRITACPIITRDPSGNCQFWGMVLLGPHHVKRDTDNAPLLIAEIM
GEDTEEKYPKHSVFSLKVEGKQFLLSLKITSFSRNKLYTFSNIRRVLIQP
ASIYSQVVLSRAAENNSLNLEVNPEIQLYLEGAQRGMTLYQWVRMILCLE
FLMAIYNNPQMEGFLANMRRLHMSRHAMMERRQVFLPFGSRPEDKVNECI
INNPIVAYLAKGWNSMPNVYY

3D structure

PDB

8p0u Thogoto virus polymerase

Chain

Resolution

2.92 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	D247 Q248 P289 D350 W352 E389 Q392 I393 T396 R397 T416 R417 D418 P419	D246 Q247 P288 D349 W351 E388 Q391 I392 T395 R396 T415 R416 D417 P418
BS02	rna	A	S268 G302 I303 N304 K305 K306 Y326 V328 H435 N442 K461 K479 I480 T481 S482	S267 G301 I302 N303 K304 K305 Y325 V327 H434 N441 K460 K478 I479 T480 S481

Gene Ontology

	Cellular Component
GO:0042025	host cell nucleus
GO:0044423	virion component

View graph for
Cellular Component

External links

PDB	RCSB:8p0u, PDBe:8p0u, PDBj:8p0u
PDBsum	8p0u
PubMed
UniProt	P27194\|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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