Structure of PDB 8p0b Chain A

Receptor sequence

>8p0bA (length=618) Species: 11569 (Thogotovirus thogotoense) [Search protein sequence]

DRPDHIDSRVWELSETQEDWITQVHGHVRRVVECWKYTICCLISNMHTGA
PQYDVFKWQDRSTIEWICSKKKVQYPERDTPDLYDNERAVAYKVLLVSDL
SDHSPTSGIYHDLAFNLEGEAEESCALVLRGSQLQDIKGFLCRALEWVVS
NNLTQEVVETISGEAKLQFSVGTTFRTLLKRDTDWDVIPTPRVEPNVPRI
EGRRWTQMKKLPLLKEKEGPPSPWRALLLGADSEYIVCPPGTDQEAISWI
HSQSEIECIRESKSTPASVITCLTSSLQSFAEGNPVRSRIHEDIIAFGIN
KKQEKKQSASSSASGEWKRAEYQVEEMSLPPWVEEEMVLLRSDQEDNWIE
LEKNAIYTEVDGVAEGLVDKYIEIVGRTKVASVIEKWQIAATRTFSQLHT
DRSRITACPIITRDPSGNCQFWGMVLLGPHHVKRDTDNAPLLIAEIMGED
TEEKYPKHSVFSLKVEGKQFLLSLKITSFSRNKLYTFSNIRRVLIQPASI
YSQVVLSRAAENNSLNLEVNPEIQLYLEGAQRGMTLYQWVRMILCLEFLM
AIYNNPQMEGFLANMRRLHMSRHAMMERRQVFLPFGSRPEDKVNECIINN
PIVAYLAKGWNSMPNVYY

3D structure

PDB

8p0b Thogoto virus polymerase

Chain

Resolution

2.87 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	D247 Q248 P289 V290 N351 W352 E389 I393 T396 R397 T416 R417 D418 P419 R495	D243 Q244 P285 V286 N347 W348 E385 I389 T392 R393 T412 R413 D414 P415 R491
BS02	rna	A	S268 G302 N304 K305 K306 Q307 K309 Y326 V328 H435 N442 K461 K479 I480 T481 S482	S264 G298 N300 K301 K302 Q303 K305 Y322 V324 H431 N438 K457 K475 I476 T477 S478

Gene Ontology

	Cellular Component
GO:0042025	host cell nucleus
GO:0044423	virion component

View graph for
Cellular Component

External links

PDB	RCSB:8p0b, PDBe:8p0b, PDBj:8p0b
PDBsum	8p0b
PubMed
UniProt	P27194\|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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