Structure of PDB 8p0a Chain A

Receptor sequence

>8p0aA (length=355) Species: 9606 (Homo sapiens) [Search protein sequence]

GFLKLIEIENFKSYKGRQIIGPFQRFTAIIGPNGSGKSNLMDAISFVLGE
KTSNLRVKTLRDLIHGAPVGKPAANRAFVSMVYSEEGAEDRTFARVIVGG
SSEYKINNKVVQLHEYSEELEKLGILIKARNFLVFQGAVESIAMKNPKER
TALFEEISRSGELAQEYDKRKKEMVKAKRAKKAKQAFEQIKKERFDRFNA
CFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRF
RPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDQIDAALDNTNIGKVAN
YIKEQSTCNFQAIVISLKEEFYTKAESLIGVYPEQGDCVISKVLTFDLTK
YPDAN

3D structure

PDB

8p0a Human Cohesin ATPase module

Chain

Resolution

3.67 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	A	K13 S14 N34 S36 G37 K38 S39 N40 R57 G67 P69 V1211	K12 S13 N33 S35 G36 K37 S38 N39 R56 G66 P68 V339
BS02	ATP	A	R1123 N1127 S1129 G1130 G1131	R251 N255 S257 G258 G259

External links

PDB	RCSB:8p0a, PDBe:8p0a, PDBj:8p0a
PDBsum	8p0a
PubMed
UniProt	Q14683\|SMC1A_HUMAN Structural maintenance of chromosomes protein 1A (Gene Name=SMC1A)

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