Structure of PDB 8oy9 Chain A

Receptor sequence

>8oy9A (length=458) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]

IMNPKRIRALKSGKQGDGPVVYWMSRDQRAEDNWALLFSRAIAKEANVPV
VVVFCLTDEFLEAGIRQYEFMLKGLQELEVSLSRKKIPSFFLRGDPGEKI
SRFVKDYNAGTLVTDFSPLRIKNQWIEKVISGISIPFFEVDAHNVVPCWE
ASQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVVETLSDVLETGVKAL
LPERALLKNKDPLFEPWHFEPGEKAAKKVMESFIADRLDSYGALRNDPTK
NMLSNLSPYLHFGQISSQRVVLEVEKAESNPGSKKAFLDEILIWKEISDN
FCYYNPGYDGFESFPSWAKESLNAHRNDVRSHIYTLEEFEAGKTHDPLWN
ASQMELLSTGKMHGYMRMYWAKKILEWSESPEKALEIAICLNDRYELDGR
DPNGYAGIAWSIGGVHDRAWGEREVTGKIRYMSYEGCKRKFDVKLYIEKY
SALDKLAA

3D structure

PDB

8oy9 Time-resolved crystallography captures light-driven DNA repair

Chain

Resolution

2.24 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

4.1.99.3: deoxyribodipyrimidine photo-lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	A160 H161 R256 E301 W305 M379 R429 W431 R441 Y442 S444 G447 R450 K451	A159 H160 R245 E290 W294 M368 R418 W420 R430 Y431 S433 G436 R439 K440
BS02	dna	A	Y158 T162 W328 R429 A430 W431 G432 E433 K439 R450	Y157 T161 W317 R418 A419 W420 G421 E422 K428 R439
BS03	FDA	A	Y252 L264 S265 N266 S268 E301 W305 K306 K372 R378 N403 D409 G410 N414 G415	Y241 L253 S254 N255 S257 E290 W294 K295 K361 R367 N392 D398 G399 N403 G404

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003904	deoxyribodipyrimidine photo-lyase activity
GO:0016829	lyase activity

	Biological Process
GO:0000719	photoreactive repair
GO:0006281	DNA repair

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8oy9, PDBe:8oy9, PDBj:8oy9
PDBsum	8oy9
PubMed	38033070
UniProt	Q8PYK9

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