Structure of PDB 8owy Chain A

Receptor sequence
>8owyA (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
AQKNWDLFYKRHWTTREQKLTMLEAGCGVGNCLFPLLEEDPNIFAYACDF
SPRAIEYVKQNPLYDTERCKVFQCDLTKDDLLDHVPPESVDVVMLIFVLS
AVHPDKMHLVLQNIYKVLKPGKSVLFRDYGLYRSYFFTDDFLAQLFMDTG
YEEVVNEYVFRRVFLQSKFLKP
3D structure
PDB8owy Structural basis of the cooperation between the m3C RNA-methyltransferase METTL6 with SerRS amino-acyl-synthetase for tRNA recognition
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A W45 Y49 W62 E85 G87 C88 G89 D110 F111 D136 L137 I157 A162 W5 Y9 W13 E24 G26 C27 G28 D49 F50 D75 L76 I96 A101
External links
PDB RCSB:8owy, PDBe:8owy, PDBj:8owy
PDBsum8owy
PubMed38918637
UniProtQ8TCB7|METL6_HUMAN tRNA N(3)-methylcytidine methyltransferase METTL6 (Gene Name=METTL6)

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