Structure of PDB 8ow4 Chain A

Receptor sequence
>8ow4A (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]
PPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQ
LHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITVTTTSYEKIVGNTK
VLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFR
VHIPESRIVSLQTASNPIECSQRSAHELPMVERQDILTGQNFESKVVFTE
WEMEATVSPVKVNFYVINGKRSQPQ
3D structure
PDB8ow4 2.75 angstrom crystal structure of human NFAT1 with bound DNA
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R421 G428 S429 R430 G431 I479 R537 Q571 R27 G34 S35 R36 G37 I85 R140 Q172
BS02 dna A Y424 T426 E427 K520 R522 N523 R537 K538 R572 Y30 T32 E33 K123 R125 N126 R140 K141 R173
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8ow4, PDBe:8ow4, PDBj:8ow4
PDBsum8ow4
PubMed
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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