Structure of PDB 8oqh Chain A

Receptor sequence
>8oqhA (length=81) Species: 9606 (Homo sapiens) [Search protein sequence]
APMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPPGKKYVRCPCN
SLLIAKVTSQRIACPRPYCKRIINLGPVHPG
3D structure
PDB8oqh Structure of the cytosolic domain of lysosome-associated TMEM55B
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.78: phosphatidylinositol-4,5-bisphosphate 4-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C91 C94 C111 C114 C6 C9 C26 C29
BS02 ZN A C132 C134 C149 C154 C47 C49 C64 C69
Gene Ontology
Molecular Function
GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
Biological Process
GO:0046856 phosphatidylinositol dephosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8oqh, PDBe:8oqh, PDBj:8oqh
PDBsum8oqh
PubMed
UniProtQ86T03|PP4P1_HUMAN Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Gene Name=PIP4P1)

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