Structure of PDB 8omz Chain A

Receptor sequence
>8omzA (length=410) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence]
RRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGI
GTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQ
TPDSKTIIISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIV
DTTPIINAHWFALPTLYTPRFEWFAILTILPAALVVIAEHVGHLVVTANI
VKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENIGVMAITRVYS
TWVIGGAAIFAILLSCVPKLAAAIQMIPLPVMGGVSLLLYGVIGASGIRV
LIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGL
SLIFKLISVL
3D structure
PDB8omz Interdomain-linkers control conformational transitions in an SLC23 elevator transporter
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DMU A F59 K62 F57 K60
BS02 DMU A L353 I354 K357 L351 I352 K355
BS03 DMU A L373 I374 V377 S378 L371 I372 V375 S376
Gene Ontology
Molecular Function
GO:0015205 nucleobase transmembrane transporter activity
GO:0015210 uracil transmembrane transporter activity
GO:0015293 symporter activity
GO:0015505 uracil:monoatomic cation symporter activity
GO:0022857 transmembrane transporter activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0015857 uracil transport
GO:0055085 transmembrane transport
GO:0098721 uracil import across plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:8omz, PDBe:8omz, PDBj:8omz
PDBsum8omz
PubMed39209842
UniProtP0AGM7|URAA_ECOLI Uracil permease (Gene Name=uraA)

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