Structure of PDB 8of7 Chain A

Receptor sequence
>8of7A (length=139) Species: 376149 (Streptomyces sp. NL15-2K) [Search protein sequence]
DVVTVELVEKVTKKDLNESGSIEGFGPGMMATYWCDVFDTEGKHIGTTVG
CMDILYADPESGHLVEHVAEQIRLPDGTIMAWGTMNRSDVLAQKWITYRC
QGTSGRYAGLVGTRTWRIQSLEDESYPIVAKMELRGALE
3D structure
PDB8of7 Interrogation of an Enzyme Library Reveals the Catalytic Plasticity of Naturally Evolved [4+2] Cyclases.
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLY A E78 Y106 W124 E70 Y98 W116
BS02 GLY A S96 D97 K102 S88 D89 K94
BS03 SER A W90 Q109 W82 Q101
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8of7, PDBe:8of7, PDBj:8of7
PDBsum8of7
PubMed37305956
UniProtA0A401MXE6

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