Structure of PDB 8kib Chain A

Receptor sequence
>8kibA (length=412) Species: 10090 (Mus musculus) [Search protein sequence]
SRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDA
TNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRN
ILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPGK
VEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMAL
SKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQKICYEHRLI
DDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGK
TVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTE
LSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKL
GENLKAKLAQAK
3D structure
PDB8kib NADP+-dependent cytosolic isocitrate dehydrogenase complexed with oxaloacetate
ChainA
Resolution1.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A T75 T77 N96 L288 H309 G310 T311 V312 T313 R314 H315 N328 T74 T76 N95 L287 H308 G309 T310 V311 T312 R313 H314 N327
BS02 OAA A T77 S94 N96 R100 R132 T76 S93 N95 R99 R131
BS03 NAP A D253 Q257 K260 D252 Q256 K259
BS04 OAA A K212 I215 K211 I214
BS05 OAA A H170 D171 H169 D170
External links
PDB RCSB:8kib, PDBe:8kib, PDBj:8kib
PDBsum8kib
PubMed
UniProtO88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Gene Name=Idh1)

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