Structure of PDB 8ki7 Chain A

Receptor sequence

>8ki7A (length=2003) Species: 36415 (Tomato spotted wilt virus (strain Bulgarian L3))

MNIQKIQKLIENGTTLLLSIEDCVGSNYDLALDLHKRNSDEIPEDVIINN
NAKNYETMRELIVKITADGEGLNKGMATVDVKKLSEMVSLFEQKYLETEL
ARHDIFGELISRHLRIKPKQRSEVEIEHALREYLDELNKKSCINKLSDDE
FERINKEYVATNATPDNYVIYKESKNSELCLIIYDWKISVDARTETKTME
KYYKNIWKSFKDIKVNGKPFLEDHPVFVSIVILKPIAGMPITVTSSRVLE
KFEDSPSALHGERIKHARNAKLLNISHVGQIVGTTPTVVRNYYANTQKIK
SEVRGILGDDFGSKDVFFSHWTSKYKERNPTEIAYSEDIERIIDSLVTDE
ITKEEIIHFLFGNFCFHIETMNDQHIADKFKGYQSSCINLKIEPKVDLAD
LKDHLIQKQQIWESLYGKHLEKIMLRIREKKKKEKEIPDITTAFNQNAAE
YEEKYPNCFTNDLSETKTNFSMTWSPSFEKINNAIINKFRESFKSSSRVI
YNSPYSTNKARDITNLVRLCLTELSCDTTKMEKQELEDEIDINTGSIKVE
RTKKSKEWNKQGSCLTRNKNEFCMKETGRENKTIYFKGLAVMNIGMSSKK
RILKKEEIKERISKGHMKKLIRHDNEDSLSWCERIKDSLFVLHNGDIREE
GKITSVYNNYAKNPECLYIQDSVLKTELETCKKINKLCNDLAIYHYSEDM
MQFSKGLMVADRYMTKESFKILTTANTSMMLLAFKGDGMNTGGSGVPYIA
LHIVDEDMSDQFNICYTKEIYSYFRNGSNYIYIMRPQRLNQVRLLSLFKT
PSKVPVCFAQFSKKANEMEKWLKNKDIEKVNVFSMTMTVKQILINIVFSS
VMIGTVTKLSRMGIFDFMRYAGFLPLSDYSNIKEYIRDKFDPDITNVADI
YFVNGIKKLLFRMEDLDIIGGITDLNIKCPITGSTLLTLEDLYNNVYLAI
YMMPKSLHNHVHNLTSLLNVPAEWELKFRKELGFNIFEDIYPKKAMFDDK
DLFSINGALNVKALSDYYLGNIENVGLMRSEIENKEDFLSPCYKISTLKS
SKKCSQSNIISTDEIIECLQNAKIQDIENWKGNNLAIIKGLIRTYNEEKN
RLVEFFEDNCVNSLYLVEKLKEIINSGSITVGKSVTSKFIRNNHPLTVET
YLKTKLYYRNNVTVLKSKKVSEELYDLVKQFHNMMEIDLDSVMNLGKGTE
GKKHTFLQMLEFVMSKAKNVTGSVDFLVSVFEKMQRTKTDREIYLMSMKV
KMMLYFIEHTFKHVAQSDPSEAISISGDNKIRALSTLSLDTITSYNDILN
KNSKKSRLAFLSADQSKWSASDLTYKYVLAIILNPILTTGEASLMIECIL
MYVKLKKVCIPTDIFLNLRKAQGTFGQNETAIGLLTKGLTTNTYPVSMNW
LQGNLNYLSSVYHSCAMKAYHKTLECYKDCDFQTRWIVHSDDNATSLIAS
GEVDKMLTDFSSSSLPEMLFRSIEAHFKSFCITLNPKKSYASSSEVEFIS
ERIVNGAIIPLYCRHLANCCTESSHISYFDDLMSLSIHVTMLLRKGCPNE
VIPFAYGAVQVQALSIYSMLPGEVNDSIRIFKKLGVSLKSNEIPTNMGGW
LTSPIEPLSILGPSSNDQIIYYNVIRDFLNKKSLEEVKDSVSSSSYLQMR
FRELKGKYEKGTLEEKDKKMIFLINLFEKASVSEDSDVLTIGMKFQTMLT
QIIKLPNFINENALNKMSSYKDFSKLYPNLKKNIASSLEMESVHDIMIKN
PETILIAPLNDRDFLLSQLFMYTSPSKRNQLSNQSTEKLALDRVLRSKAR
TKMTYEENMEKKILEMLKFDLDSYCSFKTCVNLVIKDVNFSMLIPILDSA
YPCESRKRDNYNFRWFQTEKWIPVVEGSPGLVVMHAVYGSNYIENLGLKN
IPLTDDSINVLTSTFGTGLIMEDVKSLVKGKDSFETEAFSNSNECQRLVK
ACNYMIAAQNRLLAINTCFTRKSFPFYSKFNLGRGFISNTLALLSTIYSK
EES

3D structure

• PDB: 8ki7 Structure of Tomato spotted wilt virus L protein
• Chain: A
• Resolution: 3.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	K467 M605 N606 M609 K618 K656 D775 G781 S782 R823 P824 Q825 R826 R831 K896 L897 H1015 T1018 N1022 K1191 K1291 F1428 E1432 T1433 I1435	K467 M592 N593 M596 K605 K618 D737 G743 S744 R785 P786 Q787 R788 R793 K858 L859 H962 T965 N969 K1138 K1238 F1375 E1379 T1380 I1382
BS02	rna	A	K773 D775 T1183 N1195	K735 D737 T1130 N1142
BS03	rna	A	K588 F599 S611 K612 Y751 N778 N1196 P1198 F1761 N1765 D1871	K575 F586 S598 K599 Y713 N740 N1143 P1145 F1708 N1712 D1792

External links

• PDB: RCSB:8ki7, PDBe:8ki7, PDBj:8ki7
• PDBsum: 8ki7
• UniProt: A0A7G8JUQ9