Structure of PDB 8kgr Chain A

Receptor sequence
>8kgrA (length=780) Species: 10497 (African swine fever virus) [Search protein sequence]
VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNITTDSGETIMVRNEQLTNNKVLQGIVQVL
GLDFNCHYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQ
LIIHGFVKRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLANHTVK
YYKGLAAHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKR
ELCTGVVPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLD
GMTRARRKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSI
IKAAQYYPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKT
MFPAEDSWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWA
RQLEDILALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKR
FGQYYYSYGTYVISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEE
IIDYSSSETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSH
LNFVKPKGGIIEFNTYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMET
AIVRYINESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEE
LNQKALQGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQES
PFPGASVWLEEIDAVEKAIIKGRNTQWKFH
3D structure
PDB8kgr Structure of African swine fever virus topoisomerase II in complex with dsDNA
ChainA
Resolution3.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0000819 sister chromatid segregation
GO:0006259 DNA metabolic process
GO:0006265 DNA topological change
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8kgr, PDBe:8kgr, PDBj:8kgr
PDBsum8kgr
PubMed38816407
UniProtA0A2X0THW2

[Back to BioLiP]