Structure of PDB 8kcw Chain A

Receptor sequence
>8kcwA (length=626) Species: 9606 (Homo sapiens) [Search protein sequence]
RGADFDHVYSGVVNLSTENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPV
LVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSEATNETGPLQQ
LIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFTASPSQPQYFLYKF
PKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKK
AAITLQKKDFPGEQFFVVFVIKPEDYACGGSFQTWNLQRKKNLEVTIVPS
IKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYYFWNIITIAVFYALPVIQ
LVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLF
LLIVLRRDILHRRALEAEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPN
YSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVIMVTVL
GVVFGKNDVWFWVIFSAIHVLASLALSTQIYMDRMVLLVVGNLVNWSFAL
FGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVA
TAVMWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSA
TALFFSFLVLLTLDDDLDVVRRDQIP
3D structure
PDB8kcw Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity.
ChainA
Resolution2.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H563 D574 H791 H795 H396 D407 H592 H596
BS02 CLR A Y579 M580 A599 S603 S607 F608 Y412 M413 A432 S436 S440 F441
BS03 CLR A M586 L587 Y590 Q646 M419 L420 Y423 Q479
External links
PDB RCSB:8kcw, PDBe:8kcw, PDBj:8kcw
PDBsum8kcw
PubMed38811802
UniProtQ9NXL6|SIDT1_HUMAN SID1 transmembrane family member 1 (Gene Name=SIDT1)

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