Structure of PDB 8k9s Chain A

Receptor sequence
>8k9sA (length=489) Species: 5835 (Plasmodium falciparum CAMP/Malaysia) [Search protein sequence]
VDPRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEH
LEDTILNITGRIMRVSASGQKLRFFDLVGDGEKIQVLANYSFHNHEKGNF
AECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGL
KDTEIRYRQRYLDLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPM
MNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGK
VFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYK
ISYNKDGPENQPIEIDFTPPYPKVSIVEEIEKVTNTILEQPFDSNETIEK
MINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSP
LAKYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFLDSAFCTSL
EYGLPPTGGLGLGIDRITMFLTNKNSIKDVILFPTMRPA
3D structure
PDB8k9s Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors.
ChainA
Resolution2.35 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LYS A G284 E308 E346 Y348 N503 Y505 E507 G552 G207 E231 E269 Y271 N426 Y428 E430 G459
BS02 JRU A R330 E332 G333 T337 H338 N339 F342 E500 V501 G554 G556 R559 R253 E255 G256 T260 H261 N262 F265 E423 V424 G461 G463 R466
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