Structure of PDB 8k88 Chain A

Receptor sequence

>8k88A (length=468) Species: 35554 (Geobacter sulfurreducens) [Search protein sequence]

SQLAAHSTIPEPLLLFKDNRTDTHPLRGLSQYGPYSACFNLPGQVRLAYL
APTEHMRKLDAIVRELQNPATPKEATNYYVEYGGFEKVFKVPLVMPQEHL
RCLALDECHGVAANGNGLALADKIVQSMSGLFRQKHAFDVLLVYLPASWK
KCFEYDGFDLHDRIKAKVAPLNLPIQIINDTALTRQCRANVMWGVSVALY
AKAGGIPWKLADWDKDEAYIGLSYAIKKNAEGQEYTTCCSQVFDPDGTGF
EFVAYDTREFITDRKGNPYLSYQEMQSVLSKSLHLYQSSHNGRMPRKIFI
HKTTHFTEDEIQGAFDSFSSSTEIELVQIIQSTNWYGLKVDGKKGDKPVA
PASYPVDRGLYQPLTESECLLWTQGSVMGVNQQNPGQPVFKEAALTPLPN
PIMLRRFSGNGGWHATCSSILALTKVDWNNNTLYKKLPVTLVYSQVFADV
VKQTPEIVNEIYDYRFFM

3D structure

PDB

8k88 Structural Basis of prokaryotic Argonaute System

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	E79 A80 N82 R190 Y229 A230 I231 T308 I335 Q336 S337 S358 Y359 K396 A398 A399	E74 A75 N77 R185 Y224 A225 I226 T303 I330 Q331 S332 S353 Y354 K391 A393 A394
BS02	rna	A	F158 E159 D164 H166 K170 I182 N184 A187 R190 V196 V200 Q238 Y240 G271 Y274 Q379 L400 T401 N434 N435 N436 K440 K441 M473	F153 E154 D159 H161 K165 I177 N179 A182 R185 V191 V195 Q233 Y235 G266 Y269 Q374 L395 T396 N429 N430 N431 K435 K436 M468
BS03	MG	A	N434 M473	N429 M468

Gene Ontology

	Molecular Function
GO:0003674	molecular_function

	Biological Process
GO:0008150	biological_process

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Molecular Function

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Biological Process

External links

PDB	RCSB:8k88, PDBe:8k88, PDBj:8k88
PDBsum	8k88
PubMed	38923459
UniProt	Q74DF5

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