Structure of PDB 8k69 Chain A

Receptor sequence
>8k69A (length=458) Species: 39946 (Oryza sativa Indica Group) [Search protein sequence]
YVLHSIVLIYRFVSLHVHPFWIQLSYFLLISILGSVLLMFLKPSSPEFKP
GYIDMLFLSTSAMTVSGLSTIEMEVLSSSQIVVLTLLMLVGGEVFVSFLG
LMLRLLKRSKRLRWFLGFVVFSYFVVIHVVGFLLVLWYISRVSSAKAPLK
KKGINIALFSFSVTVSSFANGGLVPTNENMAIFSKNPGLLLLFIGQILAG
NTLYPLFLRILIWFLGKVTKLKDLKLMIKNSDELQYDYLLPKLPTAFLAS
TVIGLMASLVTLFGAVDWNSSVFDGLSSYQKIINALFMAVNARHSGENSI
DCSLIAPAVLVLFIILMYLPPSTTFALSNGDEKTANKKAKRKLGLVVQNL
AFSQLACISVFVIVAFITERSRLRNDPLNFSALNMIFEIISAYGNVGLST
GYSCSRLQKLHPGSICQDKPYSLSGWWSDEGKLLLVFVMLYGRLKAFTKG
TGEYWRLW
3D structure
PDB8k69 Structural insights into ion selectivity and transport mechanism of plant HKT transporters
ChainA
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 Y01 A R281 W285 K314 S322 I325 G326 R209 W213 K242 S250 I253 G254
BS02 Y01 A H39 G416 L417 C429 Y513 F519 H18 G344 L345 C357 Y441 F447
BS03 T7X A W209 Y210 P259 G260 L263 W137 Y138 P187 G188 L191
BS04 CLR A I199 L264 G267 F279 I282 F286 I127 L192 G195 F207 I210 F214
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
Biological Process
GO:0006812 monoatomic cation transport
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8k69, PDBe:8k69, PDBj:8k69
PDBsum8k69
PubMed38570642
UniProtQ93XI5|HKT22_ORYSI Cation transporter HKT2;2 (Gene Name=HKT2;2)

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