Structure of PDB 8k4r Chain A

Receptor sequence
>8k4rA (length=506) Species: 1944 (Streptomyces halstedii) [Search protein sequence]
DHALHARFLRGLACAPDRPAVRFGGRTLTYAQAHRTALTWAGSLLRATPE
PPAAVGVLADKGIPAYLGILTALYAGAAVVPLRPDFPAARTAEMMRAAGV
TAVIADGRGRRLLPELLADRRDTAVLAADAPGRRVAIDEGYALTAPRDVV
PDDTAYVLFTSGSTGRPKGVPLSHGNIAHYFEVLDARYDFTADDVFTQTF
DLNFCCSLFDLFCAWGAGASVIQIPPQAYRDLPSHLAEQGVTVWFSTPSS
IALVRRLGGLAPGSLPTLRWSFFAGEALKCADTEDWQRAAPASFVENLYG
PTELTVTVTAHRWSPEVSPVVGANGVVPIGPLHKGLDHVLIDAGGLPHPD
TGELCVTGPQMAGRYLDPADDHGRFLDHDGRRWYRTGDRVRLAPGGELVY
LGRMDAQVQIQGWRVELAEVDHALQGCEGVGEAVTVGAATDAGTELVVFY
TAPAPVPPVRFAAVLRATLPDGVVPRHYRHVAELPLNSNRKIDRRALTAR
AEELLG
3D structure
PDB8k4r Structural Basis of Amide-Forming Adenylation Enzyme VinM in Vicenistatin Biosynthesis.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VPI A T217 F218 D219 F222 C223 C224 Y247 G430 T199 F200 D201 F204 C205 C206 Y229 G412
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0031177 phosphopantetheine binding
Biological Process
GO:0043041 amino acid activation for nonribosomal peptide biosynthetic process
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k4r, PDBe:8k4r, PDBj:8k4r
PDBsum8k4r
PubMed37870408
UniProtQ76KY3

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