Structure of PDB 8k4d Chain A

Receptor sequence
>8k4dA (length=920) Species: 9606 (Homo sapiens) [Search protein sequence]
MLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVT
AEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVL
VRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVN
VALNLSINMDNTQRQYEAERNKANERLELLLQKRKELQENQDEIENMMNA
IFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMH
DKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVA
VQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLF
SQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLL
LEEPLSALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKT
QLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRL
EKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRS
QLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSK
WDLFACNYKLLKTGIENGDMPEQIVIHALQCTHYVILWQLAKISSSTKED
LLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDILMIFSHQIMSGGR
DMLEPLVYTPDSSLQSELLSFILDHVFIEQQEDEASKIEALHKRRNLLAA
FCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAK
TLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFLKTREAIA
MLHKDGIEFAFKEPNPQGEPLNLAFLDILSEFSSKLLRQDKRTVYVYLEK
FMTFQMSLVWLPLMSYRNSL
3D structure
PDB8k4d The CENP-O complex links inner kinetochore to centromere cohesion
ChainA
Resolution3.52 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D326 W334 L366 R370 F371 D239 W247 L279 R283 F284
External links
PDB RCSB:8k4d, PDBe:8k4d, PDBj:8k4d
PDBsum8k4d
PubMed
UniProtQ8N3U4|STAG2_HUMAN Cohesin subunit SA-2 (Gene Name=STAG2)

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