Structure of PDB 8k24 Chain A

Receptor sequence

>8k24A (length=929) Species: 979527 (Vibrio phage ICP1_2004_A)

MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLI
NVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLK
QGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKG
NDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRAT
KTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKL
LATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLD
ECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFA
WQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMV
SLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQ
TSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYV
RCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISN
IFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRF
VNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLI
RTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLN
RKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQC
AGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKN
MLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVF
VGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKW
QGENGSITVPEYLLDKTICYNDFYGGYEN

3D structure

• PDB: 8k24 Structure of csy complex with long DNA State2
• Chain: A
• Resolution: 3.72 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870	M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870
BS02	dna	A	K10 Q11	K10 Q11
BS03	MN	A	D112 K115 H136 H186 H187	D112 K115 H136 H186 H187
BS04	MN	A	H111 D112 D280 H312	H111 D112 D280 H312

Gene Ontology

Molecular Function

• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0051607 defense response to virus

External links

• PDB: RCSB:8k24, PDBe:8k24, PDBj:8k24
• PDBsum: 8k24
• UniProt: F1D5V9