Structure of PDB 8jy8 Chain A

Receptor sequence
>8jy8A (length=242) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
YRDYVAEFLGNFVLIYIAKGAVITSLLVPDFGLLGLTIGIGVAVTMALYV
SLGISGGHLNSAVTVGNAVFGDFPWRKVPGYIAAQMLGTFLGAACAYGVF
ADLLKAHGGGELIAFGEKGIAWVFAMYPAEGNGIFYPIFAELISTAVLLL
CVCGIFDPNNSPAKGYETVAIGALVFVMVNNFGLASPLAMNPSLDFGPRV
FGAILLGGEVFSHANYYFWVPLVVPFFGAILGLFLYKYFLPH
3D structure
PDB8jy8 Structural insights into drug transport by an aquaglyceroporin.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PNT A V245 A259 N261 L264 V175 A189 N191 L194
Gene Ontology
Molecular Function
GO:0015204 urea transmembrane transporter activity
GO:0015250 water channel activity
GO:0015254 glycerol channel activity
Biological Process
GO:0006833 water transport
GO:0015791 polyol transmembrane transport
GO:0015793 glycerol transmembrane transport
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8jy8, PDBe:8jy8, PDBj:8jy8
PDBsum8jy8
PubMed38734677
UniProtQ6ZXT3|AQP2_TRYBB Aquaglyceroporin-2 (Gene Name=AQP2)

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