Structure of PDB 8jqz Chain A

Receptor sequence
>8jqzA (length=376) Species: 57486 (Mus musculus molossinus) [Search protein sequence]
KASSLTEFFKNFKMESKIISKETIDSIQSCIQEGDIQKVISIINAALTDI
EKAPLNIAVTGETGAGKSTFINALRGIGHEESEMDRKKYTHPKFPNVTIW
DLPGVFKPEEYLKKMKFQEYDFFLIISSARFREAQLAEAIKKMKKKFYFV
RTKIDSDLWNEKKAKPSSYNREKILEAIRSDCVKNLQSTRVFLVSSFEVA
QFDFPSLESTLLEELPAHKRHIFVQCLPTITEPAIDRRRDVLKQTIWLEA
LKAGASATIPMMSFFNDDIEEFEKILSHYRACFGLDDESLENMAKEWSMS
VEELESTIKSPHLLSSEPNESVADKLVKTMEKIFAVTGGFVATGLYFRKS
YYMQNYFLDTVTEDAKVLLKKLEHHH
3D structure
PDB8jqz Structural basis of IRGB10 oligomerization by GTP hydrolysis.
ChainA
Resolution3.05 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G78 A79 G80 S82 T83 K183 D185 S186 S230 S231 F232 G64 A65 G66 S68 T69 K153 D155 S156 S195 S196 F197
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016787 hydrolase activity
Biological Process
GO:0006952 defense response
GO:0035458 cellular response to interferon-beta
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8jqz, PDBe:8jqz, PDBj:8jqz
PDBsum8jqz
PubMed37705969
UniProtU5NFV2

[Back to BioLiP]