Structure of PDB 8joy Chain A

Receptor sequence
>8joyA (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPARLPYLRTWFRTRSAIILHLSNG
SVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSSR
3D structure
PDB8joy Crystal Structures of Plk1 Polo-Box Domain Bound to the Human Papillomavirus Minor Capsid Protein L2-Derived Peptide.
ChainA
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K413 W414 D416 Y485 S487 E488 H489 L490 L491 R516 H538 K540 R557 K41 W42 D44 Y113 S115 E116 H117 L118 L119 R138 H160 K162 R179
External links
PDB RCSB:8joy, PDBe:8joy, PDBj:8joy
PDBsum8joy
PubMed37684534
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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