Structure of PDB 8joj Chain A

Receptor sequence
>8jojA (length=523) Species: 1833 (Rhodococcus erythropolis) [Search protein sequence]
HHHHSQLENLYFQGSDWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLE
KTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARTYLRALLGDAESE
RQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDL
DPADIGDLAGKVRPELDQDRTGQDHAPGPMIGGRALIGRLLAAVQSTGKA
ELRTESVLTSLIVEDGRVVGAEVESGGETQRIKANRGVLMAAGGIEGNAE
MREQAGTPGKAIWSMGPFGANTGDAISAGIAVGGATALLDQAWFCPGVEQ
PDGSAAFMVGVRGGLVVDSAGERYLNESLPYDQFGRAMDAHDDNGSAVPS
FMIFDSREGGGLPAICIPNTAPAKHLEAGTWVGADTLEELAAKTGLPADA
LRSTVEKFNDAAKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPF
YAARIVLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASLSGRFY
PGPGVPLGTAMVFSYRAAQDMAK
3D structure
PDB8joj Crystal structure of 3-ketosteroid delta1-dehydrogenase from Rhodococcus erythropolis SQ1 in complex with 9,11-epoxy-17-hydroxypregn-4-ene-3,20-dione actate
ChainA
Resolution2.819 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.99.4: 3-oxosteroid 1-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A V31 L54 E55 K56 G62 T63 S64 S67 G68 S70 V212 L213 A247 G248 A275 N276 D279 L465 N495 G509 P511 L512 V26 L49 E50 K51 G57 T58 S59 S62 G63 S65 V207 L208 A242 G243 A270 N271 D274 L460 N490 G504 P506 L507
BS02 UU0 A G68 S70 F134 Y336 G63 S65 F129 Y331
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors
GO:0047571 3-oxosteroid 1-dehydrogenase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8joj, PDBe:8joj, PDBj:8joj
PDBsum8joj
PubMed
UniProtQ9RA02

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