Structure of PDB 8jmh Chain A

Receptor sequence
>8jmhA (length=407) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
LPNYTNLDLFHRAVFPFMFLAQCVAIMPLVGIRESNPRRVRFAYKSIPMF
VTLIFMIATSILFLSMFTHLLKIGITAKNFVGLVFFGCVLSAYVVFIRLA
KKWPAVVRIWTRTEIPFTKPPYEIPKRNLSRRVQLAALAIIGLSLGEHAL
YQVSAILSYTRRIQMCANITTVPSFNNYMQTNYDYVFQLLPYSPIIAVLI
LLINGACTFVWNYMDLFIMMISKGLSYRFEQITTRIRKLEHEEVCESVFI
QIREHYVKMCELLEFVDSAMSSLILLSCVNNLYFVCYQLLNVFNKLRWPI
NYIYFWYSLLYLIGRTAFVFLTAADINEESKRGLGVLRRVSSRSWCVEVE
RLIFQMTTQTVALSGKKFYFLTRRLLFGMAGTIVTYELVLLQFDEPNRRK
GLQPLCA
3D structure
PDB8jmh Structural basis for sugar perception by Drosophila gustatory receptors.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A F134 E196 H197 T257 Y353 F85 E147 H148 T208 Y304
BS02 FRU A G131 F134 F135 Y200 Y234 N253 G82 F85 F86 Y151 Y185 N204
Gene Ontology
Molecular Function
GO:0008527 taste receptor activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0033041 sweet taste receptor activity
GO:0170023 ionotropic sweet taste receptor activity
Biological Process
GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste
GO:0007165 signal transduction
GO:0007637 proboscis extension reflex
GO:0034220 monoatomic ion transmembrane transport
GO:0050909 sensory perception of taste
GO:0050912 detection of chemical stimulus involved in sensory perception of taste
GO:0050916 sensory perception of sweet taste
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8jmh, PDBe:8jmh, PDBj:8jmh
PDBsum8jmh
PubMed38305684
UniProtP83293|GR64A_DROME Gustatory receptor for sugar taste 64a (Gene Name=Gr64a)

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