Structure of PDB 8jl0 Chain A

Receptor sequence

>8jl0A (length=573) Species: 35554 (Geobacter sulfurreducens)

MDVLTDNEFYQHYLQNSQHMMWFLGAGTSRSAGLPTASDIIWDLKHRYYC
INNHAIKSKIQSYMDSKGFPLQWSPEEYSFYFELVFRDDYEAQRKYLLEA
LASRKVSLNIGHRVLAALLEMNQTKVVFTTNFDDVIETAFSDISGKHLSV
YHLEGSYAALSALNTEAFPIYAKIHGDFRYQKIKNLTPDLQTNDREIHKC
FLAAAIRFGLVVSGYSGRDENVMTMLRAAIDQNNAFPHGLYWTVPSISKS
EPAVQDLITYAQGKGVRAYLVETGTFDEMLSKIWRQVKDKPAAIDAKVRT
ARVCPVSIPLPGPGKSFPALRTNALPVVTQSIRCGVVTLASPITFSELKE
RISQKSPKALLTYTEKVLFLGGEPEIRKIFSNDEINSIGQYYIDEIAQSV
AASTFLKSFVEEAILTALLREKPILHRVRHRTHYAVIPNASAKDDRFLDL
RKAVGFKGDLGYITGNVTNAKELSWAEAVSIRLEERGGKLWIMLKPEIWI
KPLDRREEATDFIRSRRRYRFNQCSYQILDAWIKILFGSIGGGGTVNISC
FPDAEFKAEFEIGTRTAFSLGVG

3D structure

• PDB: 8jl0 Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system.
• Chain: A
• Resolution: 3.1 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	S357 K360 T415 F416 R442 R525 F532	S346 K349 T404 F405 R431 R514 F521
BS02	rna	A	E376 R440 E518	E365 R429 E507
BS03	NAD	A	A26 R30 P35 T36 A37 Y89 L112 N142 F143 D144 F189 G225 Y226 S227 R229 E262 F287	A26 R30 P35 T36 A37 Y78 L101 N131 F132 D133 F178 G214 Y215 S216 R218 E251 F276

Gene Ontology

Molecular Function

• GO:0003674 molecular_function

Biological Process

• GO:0008150 biological_process

Cellular Component

• GO:0005575 cellular_component

External links

• PDB: RCSB:8jl0, PDBe:8jl0, PDBj:8jl0
• PDBsum: 8jl0
• PubMed: 38200015
• UniProt: Q74DF6