Structure of PDB 8jkv Chain A

Receptor sequence
>8jkvA (length=527) Species: 9606 (Homo sapiens) [Search protein sequence]
AELKMDQALLLIHNELLWTNLTVYWKSECCYHCLFQVLVNVPQSPKAGKP
SAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEFGNYSLLVKNIEIAC
DLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLPRLRSVDTFRGIAL
ILMVFVNYGGGKYWYFKHASWNGLTVADLVFPWFVFIMGSSIFLSMTSIL
QRGCSKFRLLGKIAWRSFLLICIGIIIVNPNYCLGPLSWDKVRIPGVLQR
LGVTYFVVAVLELLFAKPVPECLSLRDITSSWPQWLLILVLEGLWLGLTF
LLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPSS
AVLYHTEVAYDPEGILGTINSIVMAFLGVQAGKILLYYKARTKDILIRFT
AWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFAFFILLVLY
PVVDVKGLWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEH
LTQNIVATALWVLIAYILYRKKIFWKI
3D structure
PDB8jkv membrane proteins
ChainA
Resolution2.87 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.78: heparan-alpha-glucosaminide N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A V426 G429 L437 V290 G293 L301
Gene Ontology
Molecular Function
GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0007041 lysosomal transport
GO:0030200 heparan sulfate proteoglycan catabolic process
GO:0051259 protein complex oligomerization
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0035579 specific granule membrane
GO:0043202 lysosomal lumen
GO:0070821 tertiary granule membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8jkv, PDBe:8jkv, PDBj:8jkv
PDBsum8jkv
PubMed
UniProtQ68CP4|HGNAT_HUMAN Heparan-alpha-glucosaminide N-acetyltransferase (Gene Name=HGSNAT)

[Back to BioLiP]