Structure of PDB 8jff Chain A

Receptor sequence
>8jffA (length=274) Species: 362663 (Escherichia coli 536) [Search protein sequence]
RTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNEMRC
IEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSV
VGADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDP
REVHFLYANSYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLR
RDGKLPSDLAIATFGDNELLDFLQCPVLAVAQRHRDVAERVLEIVLASLD
EPRKPKPGLTRIKRNLYRRGVLSR
3D structure
PDB8jff Sulisobenzone is a potent inhibitor of the global transcription factor Cra.
ChainA
Resolution2.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EPE A S75 A290 Q291 R323 S16 A231 Q232 R264
BS02 EPE A L278 F281 Q283 L219 F222 Q224
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0009750 response to fructose

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Molecular Function
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Biological Process
External links
PDB RCSB:8jff, PDBe:8jff, PDBj:8jff
PDBsum8jff
PubMed37805153
UniProtA0A454A0X5

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