Structure of PDB 8jev Chain A

Receptor sequence
>8jevA (length=556) Species: 10090 (Mus musculus) [Search protein sequence]
YDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWLVVTL
TGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWPQWKTWAELI
IGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGSGIPEIKTI
LSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVACCCGNIFS
YLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLK
TLWRSFFAALVAAFVLRSINPTPWYLFELFPFILLGVFGGLWGAFFIRAN
IAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFT
DCGYSAIWQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGI
AVEQLAYYHHDWFIFKITPGLYAMVGAAACLGGVTRMTVSLVVIVFELTG
GLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLDATTLAADVM
RPRSILDMSPFTVTDHTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKD
ILRHMA
3D structure
PDB8jev Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger.
ChainA
Resolution3.06 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CL A G280 K281 E282 F527 G183 K184 E185 F384
BS02 CL A S239 Y630 S142 Y478
External links
PDB RCSB:8jev, PDBe:8jev, PDBj:8jev
PDBsum8jev
PubMed39107281
UniProtP51791|CLCN3_MOUSE H(+)/Cl(-) exchange transporter 3 (Gene Name=Clcn3)

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