Structure of PDB 8jek Chain A

Receptor sequence

>8jekA (length=540) Species: 376620 (Gluconobacter japonicus)

NETLSADVVIIGAGICGSLLAHKLVRNGLSVLLLDAGPRRDRSQIVENWR
NMPPDNKSQYDYATPYPSVPWAPHTNYFPDNNYLIVKGPDRTAYKQGIIK
GVGGTTWHWAASSWRYLPNDFKLHSTYGVGRDYAMSYDELEPYYYEAECE
MGVMGPNGEEITPSAPRQNPWPMTSMPYGYGDRTFTEIVSKLGFSNTPVP
QARNSRPYDGRPQCCGNNNCMPICPIGAMYNGVYAAIKAEKLGAKIIPNA
VVYAMETDAKNRITAISFYDPDKQSHRVVAKTFVIAANGIETPKLLLLAA
NDRNPHGIANSSDLVGRNMMDHPGIGMSFQSAEPIWAGGGSVQMSSITNF
RDGDFRSEYAATQIGYNNTAQNSRAGMKALSMGLVGKKLDEEIRRRTAHG
VDIYANHEVLPDPNNRLVLSKDYKDALGIPHPEVTYDVGEYVRKSAAISR
QRLMDIAKAMGGTEIEMTPYFTPNNHITGGTIMGHDPRDSVVDKWLRTHD
HSNLFLATGATMAASGTVNSTLTMAALSLRAADAILNDLK

3D structure

• PDB: 8jek Essential Insight of Direct Electron Transfer-Type Bioelectrocatalysis by Membrane-Bound d-Fructose Dehydrogenase with Structural Bioelectrochemistry.
• Chain: A
• Resolution: 2.7 Å

Enzymatic activity

• Enzyme Commision number: 1.1.5.14: fructose 5-dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	I13 G14 G16 I17 D37 A38 K102 G103 G106 T107 T108 H110 W111 A112 S114 A252 V254 A289 N290 E293 N477 N521 T523	I11 G12 G14 I15 D35 A36 K100 G101 G104 T105 T106 H108 W109 A110 S112 A250 V252 A287 N288 E291 N475 N519 T521
BS02	F3S	A	R205 C216 C217 G218 N219 N220 N221 C222 C226 I228 M231 G342	R203 C214 C215 G216 N217 N218 N219 C220 C224 I226 M229 G340

Gene Ontology

Molecular Function

• GO:0016491 oxidoreductase activity
• GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
• GO:0047904 fructose 5-dehydrogenase activity
• GO:0050660 flavin adenine dinucleotide binding

Biological Process

• GO:0006000 fructose metabolic process

Cellular Component

• GO:0005886 plasma membrane

External links

• PDB: RCSB:8jek, PDBe:8jek, PDBj:8jek
• PDBsum: 8jek
• UniProt: M1VMF7|FDHL_GLUJA Fructose dehydrogenase large subunit (Gene Name=fdhL)