Structure of PDB 8jds Chain A

Receptor sequence
>8jdsA (length=456) Species: 10090 (Mus musculus) [Search protein sequence]
LSQDFVEALKAVVGSPHVSTASAVREQHGHDESMHRCQPPDAVVWPQNVD
QVSRVASLCYNQGVPIIPFGTGTGVEGGVCAVQGGVCINLTHMDQITELN
TEDFSVVVEPGVTRKALNTHLRDSGLWFPVDPGADASLCGMAATGASGTN
AVRYGTMRDNVINLEVVLPDGRLLHTAGRGRHYRKSAAGYNLTGLFVGSE
GTLGIITSTTLRLHPAPEATVAATCAFPSVQAAVDSTVQILQAAVPVARI
EFLDDVMMDACNRHSKLNCPVAPTLFLEFHGSQQTLAEQLQRTEAITQDN
GGSHFSWAAEKRNELWAARHNAWYAALALSPGSKAYSTDVCVPISRLPEI
LVETKEEIKASKLTGAIVGHVGDGNFHCILLVDPDDAEEQRRVKAFAENL
GRRALALGGTCTGEHGIGLGKRQLLQEEVGPVGVETMRQLKNTLDPRGLM
NPGKVL
3D structure
PDB8jds Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids containing hydrophobic moieties and plays an important role in the pathogenesis of D-lactic acidosis
ChainA
Resolution1.636 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.2.4: D-lactate dehydrogenase (cytochrome).
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004458 D-lactate dehydrogenase (cytochrome) activity
GO:0005515 protein binding
GO:0008720 D-lactate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0006754 ATP biosynthetic process
GO:1903457 lactate catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8jds, PDBe:8jds, PDBj:8jds
PDBsum8jds
PubMed37863926
UniProtQ7TNG8|LDHD_MOUSE Probable D-lactate dehydrogenase, mitochondrial (Gene Name=Ldhd)

[Back to BioLiP]