Structure of PDB 8jbb Chain A

Receptor sequence
>8jbbA (length=461) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
DLDALWERYREAVRAGGNPQALYQEMVWPALLALWREKPRVYFPQAFAVS
VHTLGTSPEATALAILGAGAERVYVLHTPESARFLPRLRQDTGKDLYPVE
IGKSDVEAIYREVKRLLEKHPEVPVALDLTSGTKAMSAGLAAAGFFFQRF
YPKVRVVYVDNEDYDPELRRPRAGTEKLRILPNPHEALAEVDALFAKELY
GKGEFGQAAAYFRGMVGRTGNQAYALYALLAEMYRAWRALDFGEALKAGR
KLLGQLSQNVWLNHPLNARREALEAQVALLEAVDRFLKARDFALKEGVYG
LARTLLHLAQEAKEEAAVLAALYAYRALELLLQERLALLGRRAEAPGLSP
EEAEALRKALAELLGVLPEEVRLPAKLGLLDLLAFLRLKGDEALGRLSLA
ELRGLAGALKGRNSALLVHGFDVPSPKAVEGIARLAQGLLQDLEARTALG
PLSPEPVPLGF
3D structure
PDB8jbb Crystal Structure of the TtCsm6 from Thermus thermophilus HB8 in complex with A2>p
ChainA
Resolution1.81 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A G58 T59 S60 T81 E83 K106 G135 T136 K137 G55 T56 S57 T78 E80 K103 G132 T133 K134
BS02 rna A S60 A63 T133 Y161 Y167 R172 R173 P174 E179 S57 A60 T130 Y158 Y164 R169 R170 P171 E176
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8jbb, PDBe:8jbb, PDBj:8jbb
PDBsum8jbb
PubMed38177499
UniProtQ53W17|CSM6_THET8 CRISPR system endoribonuclease Csm6 (Gene Name=csm6)

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