Structure of PDB 8jaz Chain A

Receptor sequence

>8jazA (length=479) Species: 1328314 (Azotobacter chroococcum NCIMB 8003) [Search protein sequence]

MDFDVKDFGAKGDGKSDDTEAIQAAIDAAYEAGGGTVRLSAGEYRVSGGD
EASDGALMIKSNVYMDGAGMGETVIKLVDGWDQKLTGIIRSKNGEKTHDY
GIRDLTLDGNQDNTEGEVDGFYTGYIPREDGADYNVTAERVEIREVSRYG
FDPHEQTINLTIRDSVAHNNGKDGFVGDFQIDSTFENNVSHDNGRHGFNI
VTSSHDILLRDNVAYGNGANGLVVQRGSEDIAHPYNIQIEGGAYHDNGAE
GVLIKMTSNASLQGAEIYGNDAAGVRVRGVDGMQLLDNDIHDNAQGGGKA
EIVLEDYDDRDGVSGNYYETLNATVQGNRVAGAAQLLSSEGRDLLDGAAG
NDLLDGGAGRDTLSGGGGADTFRFADRQDSFRNYEGDTSRVDDIVDFTPG
ADLIDLSGLGYSGLGDGYNGTLALLLNEDGTKTYLKDRQADAQGNHFEIA
LDGNLVDSLSATDIAFDATQLELLGTTDL

3D structure

PDB

8jaz Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum.

Chain

Resolution

1.82 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

5.1.3.37: mannuronan 5-epimerase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	A	D66 G67 D104	D66 G67 D104
BS02	CA	A	S91 X92 E95 T97 G124 D133	S91 X92 E95 T97 G124 D133
BS03	CA	A	S339 G341 D343 G356 A358 D361	S339 G341 D343 G356 A358 D361
BS04	CA	A	G357 G359 D361 D379 D392	G357 G359 D361 D379 D392
BS05	CA	A	G366 G367 G368 D370 D402	G366 G367 G368 D370 D402
BS06	CA	A	A348 G350 D352 G365 G367 D370	A348 G350 D352 G365 G367 D370

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0016829	lyase activity
GO:0016853	isomerase activity
GO:0046872	metal ion binding

	Biological Process
GO:0042121	alginic acid biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8jaz, PDBe:8jaz, PDBj:8jaz
PDBsum	8jaz
PubMed	38649293
UniProt	A0A0C4WKK2

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