Structure of PDB 8ja2 Chain A

Receptor sequence
>8ja2A (length=387) Species: 10497 (African swine fever virus) [Search protein sequence]
AFEISDFKEHAKKKSMWAGALNKVTISGLMGVFTEDEDLMALPIHRDHCP
ALLKIFDELIVNATDHERACHSKTKKVTYIKISFDKGVFSCENDGPGIPI
AKHEQASLIAKRDVYVPEVASCFFLAGTNINKAKDCIKGGTNGVGLKLAM
VHSQWAILTTADGAQKYVQQINQRLDIIEPPTITPSREMFTRIELMPVYQ
ELGYAEPLSETEQADLSAWIYLRACQCAAYVGKGTTIYYNDKPCRTGSVM
ALAKMYTLLSAPNSTIHTATIKADAKPYSLHPLQVAAVVSPKFKKFEHVS
IINGVNCVKGEHVTFLKKTINEMVIKKFQQSCSNIFVVIVGSIPGIEWTG
QRKDELSIAENVFKTHYSIPSSFLTSMTRSIVDILLQ
3D structure
PDB8ja2 ASFV Topoisomerase ATPase domain in complex with AMP-PNP and Mg2+
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A N64 H68 N95 A122 T130 N131 G142 T143 N144 G145 V146 G147 L148 K149 K368 N62 H66 N93 A120 T128 N129 G140 T141 N142 G143 V144 G145 L146 K147 K353
External links
PDB RCSB:8ja2, PDBe:8ja2, PDBj:8ja2
PDBsum8ja2
PubMed38418525
UniProtQ00942|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

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