Structure of PDB 8j6o Chain A

Receptor sequence
>8j6oA (length=648) Species: 6100,9606 [Search protein sequence]
PKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNK
QKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNE
SEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYF
KYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQT
MTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQG
HRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQTI
AVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSN
LGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTA
LMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASA
YSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYML
YVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYI
IMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHN
RDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF
3D structure
PDB8j6o transport T2
ChainA
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H568 H796 H800 H412 H612 H616
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0035612 AP-2 adaptor complex binding
GO:0035650 AP-1 adaptor complex binding
GO:0051032 nucleic acid transmembrane transporter activity
GO:0051033 RNA transmembrane transporter activity
Biological Process
GO:0000902 cell morphogenesis
GO:0003323 type B pancreatic cell development
GO:0006091 generation of precursor metabolites and energy
GO:0006401 RNA catabolic process
GO:0008218 bioluminescence
GO:0009749 response to glucose
GO:0042593 glucose homeostasis
GO:0044342 type B pancreatic cell proliferation
GO:0050658 RNA transport
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
Cellular Component
GO:0005575 cellular_component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8j6o, PDBe:8j6o, PDBj:8j6o
PDBsum8j6o
PubMed38664565
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q8NBJ9|SIDT2_HUMAN SID1 transmembrane family member 2 (Gene Name=SIDT2)

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