Structure of PDB 8j3t Chain A

Receptor sequence
>8j3tA (length=213) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
TPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQVALPLNINHDDTAVV
GHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDK
VVEFLSGSYAGLSLSSRTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFP
DLTAADRDGLRAQWQRSGDPFRSDSYGLLGNSVDALYIRERLPKLRYDKQ
LVGVTERESYVKA
3D structure
PDB8j3t Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 T1F A E31 N62 H63 S132 L133 S134 S135 V163 G164 R165 D227 I231 E20 N43 H44 S113 L114 S115 S116 V128 G129 R130 D184 I188
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:8j3t, PDBe:8j3t, PDBj:8j3t
PDBsum8j3t
PubMed37974946
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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