Structure of PDB 8j3s Chain A

Receptor sequence
>8j3sA (length=220) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
TPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAVALPLNINHDDTAVVG
HVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFP
DLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERL
PKLRYDKQLVGVTEESYVKA
3D structure
PDB8j3s Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases
ChainA
Resolution3.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.97: assemblin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N62 H63 S132 L133 S134 S135 K156 C161 G164 R165 D227 I231 K237 N42 H43 S112 L113 S114 S115 K121 C126 G129 R130 D192 I196 K202
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8j3s, PDBe:8j3s, PDBj:8j3s
PDBsum8j3s
PubMed37974946
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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