Structure of PDB 8j2w Chain A

Receptor sequence

>8j2wA (length=330) Species: 103733 (Saccharothrix syringae) [Search protein sequence]

DILAAGREELMAALAEGDEHAAVDLAMRLLDGGVPADVVLLELVADAQVE
IGVLWQANRWSVAQEHAATAISERVIAAVGDRAAAAPTRGHVVVACLDGE
WHALPARIVAEVLRGRGWRVTFLGASVPAAHLVPYLEEHGPDAVALSCTL
PRGLPRADQVVAACRATGTPVLVGGLGFGPDGRWARVLGAGTWAPTARAA
ADLLDRPEPRPADPEYAALRARRAELVDAGLAALHEWFPPLRDYDARRLD
ATLDDLGDIVDHLAASVYVDDPELFGEFVTWTAEVLAARGVSPASVEVAL
EAIARVLDDHPRTRHHLDHGRRALAAHLEH

3D structure

PDB

8j2w Photocobilins integrate B12 and bilin photochemistry for enzyme control.

Chain

Resolution

1.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	B12	A	A51 Q54 G58 Q62 E71 T75 E79 W107 H108 A109 L110 P111 I114 V115 A151 L152 S153 L156 L178 V179 G180 G181 L182 P201 T202 A203 W296	A45 Q48 G52 Q56 E65 T69 E73 W101 H102 A103 L104 P105 I108 V109 A145 L146 S147 L150 L172 V173 G174 G175 L176 P195 T196 A197 W281
BS02	BLA	A	W61 Y259 R262 A266 T267 D270 D273 W296 V300 L301 R304 S310	W55 Y244 R247 A251 T252 D255 D258 W281 V285 L286 R289 S295

Gene Ontology

	Molecular Function
GO:0031419	cobalamin binding
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:8j2w, PDBe:8j2w, PDBj:8j2w
PDBsum	8j2w
PubMed	38548733
UniProt	A0A5Q0H231

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