Structure of PDB 8j0t Chain A

Receptor sequence
>8j0tA (length=517) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQE
LLEFPGGILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSVPVGD
GFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIK
AIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRC
VYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAASESAGFKWLAPYTGS
AIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYL
HSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCF
LETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELE
AFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGG
HLDSVPVEDVRRFETELLDHMRASEEEILTEIRDSQKLTEEAADKLTEVI
KNFKKGFAATGGGSVVP
3D structure
PDB8j0t Structure of Mycobacterium tuberculosis ATP synthase
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.2.2: H(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A K175 G177 K178 T179 A180 F360 R365 Q435 K171 G173 K174 T175 A176 F356 R361 Q431
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j0t, PDBe:8j0t, PDBj:8j0t
PDBsum8j0t
PubMed38961288
UniProtP9WPU7|ATPA_MYCTU ATP synthase subunit alpha (Gene Name=atpA)

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