Structure of PDB 8izk Chain A

Receptor sequence
>8izkA (length=223) Species: 9913 (Bos taurus) [Search protein sequence]
IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRL
GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRV
ASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKS
AYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQK
NKPGVYTKVCNYVSWIKQTIASN
3D structure
PDB8izk Structural basis for the binding of famotidine, cimetidine, guanidine, and pimagedine with serine protease.
ChainA
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E70 N72 V75 E80 E52 N54 V57 E62
BS02 GAI A D189 S190 W215 D171 S172 W193
External links
PDB RCSB:8izk, PDBe:8izk, PDBj:8izk
PDBsum8izk
PubMed39216203
UniProtP00760|TRY1_BOVIN Serine protease 1 (Gene Name=PRSS1)

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