Structure of PDB 8izi Chain A

Receptor sequence
>8iziA (length=223) Species: 9913 (Bos taurus) [Search protein sequence]
IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRL
GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRV
ASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKS
AYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQK
NKPGVYTKVCNYVSWIKQTIASN
3D structure
PDB8izi Structural basis for the binding of famotidine, cimetidine, guanidine, and pimagedine with serine protease.
ChainA
Resolution2.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E70 N72 V75 E80 E52 N54 V57 E62
BS02 SD9 A D189 S190 C191 Q192 G216 G219 C220 D171 S172 C173 Q174 G194 G196 C197
External links
PDB RCSB:8izi, PDBe:8izi, PDBj:8izi
PDBsum8izi
PubMed39216203
UniProtP00760|TRY1_BOVIN Serine protease 1 (Gene Name=PRSS1)

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