Structure of PDB 8iyf Chain A

Receptor sequence
>8iyfA (length=475) Species: 264445 (Streptomyces hygroscopicus subsp. limoneus) [Search protein sequence]
GSEIFLASKRAAITYDTDPATGEPRAWLAPGGTGNVVAEQAGVLNISWIA
SADSEDDRRASALNPDGVTMELHSGREILVRLIRHDPAVFRNVQNFMTAN
LMWAANNYGWDRWTQPSFGSDAREGWADFGRFTRDFADAILKSSAQSADP
VYLVHDYQLVGVPALLREQRPDAPILLFVAIPWPSADYWRILPKEIRTGI
LHGMLPATTIGFFADRWCRNFLESVADLLPDARIDREAMTVEWRGHRTRL
RTMPLGYSPLTLPQLPEGIEEWADGHRLVVHSGRTDPIKNAERAVRAFVL
AARGGGLEKTRMLVRMNPNRLYVPANADYVHRVETAVAEANAELGSDTVR
IDNDNDVNHTIACFRRADLLIFNSTVDGQNLSTFEAPLVNERDADVILSE
TCGAAEVLGEYCRSVNPFDLVEQAEAISAALAAGPRQRAEAAARRRDAAR
PWTLEAWVQAQLDGLAADHAARTAT
3D structure
PDB8iyf Structure of VldE-H182A in complex with GDP
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.135: validamine 7-phosphate valienyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A R290 K295 N323 N361 D362 V363 T366 N386 L387 S388 E391 R284 K289 N317 N355 D356 V357 T360 N380 L381 S382 E385
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005992 trehalose biosynthetic process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8iyf, PDBe:8iyf, PDBj:8iyf
PDBsum8iyf
PubMed
UniProtQ15JG1|VLDE_STRHL Validamine 7-phosphate valienyltransferase (Gene Name=vldE)

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