Structure of PDB 8iye Chain A

Receptor sequence
>8iyeA (length=475) Species: 264445 (Streptomyces hygroscopicus subsp. limoneus) [Search protein sequence]
GSEIFLASKRAAITYDTDPATGEPRAWLAPGGTGNVVAEQAGVLNISWIA
SADSEDDRRASALNPDGVTMELHSGREILVRLIRHDPAVFRNVQNFMTAN
LMWAANNYGWDRWTQPSFGSDAREGWADFGRFTRDFADAILKSSAQSADP
VYLVHNYQLVGVPALLREQRPDAPILLFVHIPWPSADYWRILPKEIRTGI
LHGMLPATTIGFFADRWCRNFLESVADLLPDARIDREAMTVEWRGHRTRL
RTMPLGYSPLTLPQLPEGIEEWADGHRLVVHSGRTDPIKNAERAVRAFVL
AARGGGLEKTRMLVRMNPNRLYVPANADYVHRVETAVAEANAELGSDTVR
IDNDNDVNHTIACFRRADLLIFNSTVDGQNLSTFEAPLVNERDADVILSE
TCGAAEVLGEYCRSVNPFDLVEQAEAISAALAAGPRQRAEAAARRRDAAR
PWTLEAWVQAQLDGLAADHAARTAT
3D structure
PDB8iye Structure of VldE-D158N in complex with GDP
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.135: validamine 7-phosphate valienyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A R290 K295 N323 D360 N361 T366 N386 L387 S388 E391 R284 K289 N317 D354 N355 T360 N380 L381 S382 E385
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005992 trehalose biosynthetic process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8iye, PDBe:8iye, PDBj:8iye
PDBsum8iye
PubMed
UniProtQ15JG1|VLDE_STRHL Validamine 7-phosphate valienyltransferase (Gene Name=vldE)

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